Charles Robert Scriver CC GOQ FRS FRSC (November 7, 1930 – April 7, 2023) was a Canadian pediatrician and biochemical geneticist. His work focused on inborn errors of metabolism and led in establishing a Canada-wide newborn metabolic screening program.

Charles Scriver
Born
Charles Robert Scriver

(1930-11-07)November 7, 1930
Montreal, Quebec, Canada
DiedApril 7, 2023(2023-04-07) (aged 92)
Montreal, Quebec, Canada
Alma materMcGill University
Known forInborn errors of metabolism
AwardsE. Mead Johnson Award (1968)
William Allan Award (1978)
John Howland Award (2010)
Scientific career
FieldsPediatrics
Biochemical genetics
InstitutionsMcGill University

Early life and education

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Born in Montreal, Quebec, Scriver graduated with a Bachelor of Arts in 1951 and from the Faculty of Medicine of McGill University in 1955.

Scientific career

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Scriver was appointed to the Department of Paediatrics at McGill and as a Markle scholar in 1961, becoming a professor in pediatrics in 1969. He was the Samuel Rudin Distinguished Visiting Professorship at Columbia University from 1979 to 1980 and was the Alva professor Emeritus of Human Genetics in the Faculty of Medicine of McGill University.

In 1969 he discovered that rickets could be caused by vitamin D deficiency among poorer children who drank bottled milk instead of infant formula. He persuaded Quebec suppliers to add vitamin D to their milk, leading to a decrease in the rate of rickets.[1]

Scriver played a critical role in developing scientific and ethical policies associated with the international Human Genome Project - created to decode more than three billion DNA base pairs and identify all human genes.[2][3]

Scriver was co-editor of the authoritative multi-volume textbook entitled The Metabolic & Molecular Bases of Inherited Disease, published by McGraw-Hill.

Death

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Scriver died in Montreal on April 7, 2023, at the age of 92.[4]

Honours

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Honorary degrees

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References

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  1. ^ Leung, Wency (5 May 2023). "Dr. Charles Scriver was a pioneer of medical genetics". The Globe and Mail. Retrieved 10 January 2024. after discovering vitamin D deficiency was the cause of rickets among poorer children who were fed milk instead of infant formula, Dr. Scriver enlisted the help of Arnold Steinberg of Steinberg's grocery chain to demand that Quebec milk suppliers add vitamin D
  2. ^ Western University 2007 Convocation
  3. ^ Leung, Wency (5 May 2023). "Dr. Charles Scriver was a pioneer of medical genetics". The Globe and Mail. Retrieved 10 January 2024. Scriver also played a role in initiating The Human Genome Project, ... In 1986, while at the Howard Hughes Medical Institute in the U.S., he brought together key researchers and funders for a meeting to pursue the project,
  4. ^ "In memoriam: Charles R. Scriver". McGill University Faculty of Medicine and Health Sciences. April 18, 2023. Retrieved April 19, 2023.
  5. ^ Pierre Dansereau, Charles Scriver Inducted Into The Canadian Science and Engineering Hall of Fame Archived 2013-10-17 at the Wayback Machine, News Release, Canada Science and Technology Museum, November 8, 2001.
  6. ^ "Pediatric Chairs of Canada". paediatricchairs.ca. Retrieved August 26, 2020.
  7. ^ UWO List of Honorary degrees Archived 2012-02-12 at the Wayback Machine