Carbohydrate (chondroitin 4) sulfotransferase 13

Carbohydrate (chondroitin 4) sulfotransferase 13 is a protein that is encoded in humans by the CHST13 gene.[5]

CHST13
Identifiers
AliasesCHST13, C4ST3, carbohydrate sulfotransferase 13, Carbohydrate (chondroitin 4) sulfotransferase 13
External IDsOMIM: 610124; MGI: 1919047; HomoloGene: 44360; GeneCards: CHST13; OMA:CHST13 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_152889

NM_027928

RefSeq (protein)

NP_690849

NP_082204

Location (UCSC)Chr 3: 126.52 – 126.54 MbChr 6: 90.29 – 90.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000180767Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000056643Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Carbohydrate (chondroitin 4) sulfotransferase 13".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.