C-type lectin domain family 2 member B is a protein that in humans is encoded by the CLEC2B gene.[3][4]

CLEC2B
Identifiers
AliasesCLEC2B, AICL, CLECSF2, HP10085, IFNRG1, C-type lectin domain family 2 member B
External IDsOMIM: 603242; HomoloGene: 68443; GeneCards: CLEC2B; OMA:CLEC2B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005127

n/a

RefSeq (protein)

NP_005118

n/a

Location (UCSC)Chr 12: 9.85 – 9.87 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) protein superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length nucleotide sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.[4]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000110852Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Hamann J, Montgomery KT, Lau S, Kucherlapati R, van Lier RA (Mar 1997). "AICL: a new activation-induced antigen encoded by the human NK gene complex". Immunogenetics. 45 (5): 295–300. doi:10.1007/s002510050208. PMID 9038101. S2CID 34214844.
  4. ^ a b "Entrez Gene: CLEC2B C-type lectin domain family 2, member B".
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Further reading

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