C52 or C-52 may refer to:
- C-52 (cipher machine)
- ARM General Manuel E. Rincón (C52), an Admirable-class minesweeper of the Mexican Navy
- Caldwell 52, an elliptical galaxy
- Company C, 52d Infantry Regiment (Anti-Tank) of the United States Army
- Courage C52, a French racing car
- Douglas C-52, an American transport aircraft
- Evans Gambit, a chess opening
- HMS Bermuda (C52), a Fiji-class light cruiser of the Royal Navy
- Ikarus C52, German ultralight aircraft
- JNR Class C52, a Japanese steam locomotive
- Vaginal cancer
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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