C-C motif chemokine ligand 24

C-C motif chemokine ligand 24 is a protein that in humans is encoded by the CCL24 gene. [5]

CCL24
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCCL24, Ckb-6, MPIF-2, MPIF2, SCYA24, C-C motif chemokine ligand 24
External IDsOMIM: 602495; MGI: 1928953; HomoloGene: 2248; GeneCards: CCL24; OMA:CCL24 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002991
NM_001371193

NM_019577
NM_001356630

RefSeq (protein)

NP_002982
NP_001358122

NP_062523
NP_001343559

Location (UCSC)Chr 7: 75.81 – 75.82 MbChr 5: 135.6 – 135.6 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. [provided by RefSeq, Jul 2008].

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000106178Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000004814Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: C-C motif chemokine ligand 24". Retrieved 2018-05-09.

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.