Brain-specific angiogenesis inhibitor 2

Brain-specific angiogenesis inhibitor 2 is a protein that in humans is encoded by the BAI2 gene.[5][6] It is a member of the adhesion-GPCR family of receptors.[7]

ADGRB2
Identifiers
AliasesADGRB2, BAI2, adhesion G protein-coupled receptor B2
External IDsOMIM: 602683; MGI: 2451244; HomoloGene: 1288; GeneCards: ADGRB2; OMA:ADGRB2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001294335
NM_001294336
NM_001364857

RefSeq (protein)

NP_001281264
NP_001281265
NP_001351786

Location (UCSC)Chr 1: 31.73 – 31.76 MbChr 4: 129.88 – 129.92 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

BAI1, a p53-target gene, encodes brain-specific angiogenesis inhibitor, a seven-span transmembrane protein and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities and may also play a role in angiogenesis.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000121753Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028782Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Shiratsuchi T, Nishimori H, Ichise H, Nakamura Y, Tokino T (Apr 1998). "Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)". Cytogenet Cell Genet. 79 (1–2): 103–8. doi:10.1159/000134693. PMID 9533023.
  6. ^ a b "Entrez Gene: BAI2 brain-specific angiogenesis inhibitor 2".
  7. ^ Stacey, edited by Simon Yona, Martin (2010). Adhesion-GPCRs : structure to function. New York: Springer Science+Business Media. ISBN 9781441979124. {{cite book}}: |first= has generic name (help)CS1 maint: multiple names: authors list (link)
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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.