"Big Sam" is a nickname for:
- Big Sam (musician), New Orleans trombone player of "Big Sam's Funky Nation"
- Sam Allardyce (born 1954), English football player and manager
- Big Sam (American football) (fl. 1899–1900), college football player
- Sam Thompson (1860–1922), baseball player
- Sam McDonald (1762–1802), an unusually tall Scottish soldier
- Sam Houston High School (Arlington, Texas), United States
This disambiguation page lists articles associated with the title Big Sam.
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