Big Brother 15 is the fifteenth season of various versions of Big Brother and may refer to:
- Big Brother 15 (U.S.), the 2013 edition of the U.S. version
- Big Brother 15 (UK), the 2014 edition of the UK version
- Gran Hermano 15, the 2014 edition of the Spanish version
- Big Brother Brasil 15, the 2015 edition of the Brazilian version
- Bigg Boss 15, fifteenth season of Big Brother in India in Hindi