Benzoyl-CoA 2,3-dioxygenase (EC 1.14.12.21, benzoyl-CoA dioxygenase/reductase, BoxBA, BoxA/BoxB system) is an enzyme with systematic name benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-hydroxylating).[1][2][3] This enzyme catalyses the following chemical reaction
| Benzoyl-CoA 2,3-dioxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.12.21 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- benzoyl-CoA + NADPH + H+ + O2 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP+
Benzoyl-CoA 2,3-dioxygenase is involved in aerobic benzoate metabolism in Azoarcus evansii.
References edit
- ^ Zaar A, Gescher J, Eisenreich W, Bacher A, Fuchs G (October 2004). "New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii". Molecular Microbiology. 54 (1): 223–38. doi:10.1111/j.1365-2958.2004.04263.x. PMID 15458418.
- ^ Gescher J, Zaar A, Mohamed M, Schägger H, Fuchs G (November 2002). "Genes coding for a new pathway of aerobic benzoate metabolism in Azoarcus evansii". Journal of Bacteriology. 184 (22): 6301–15. doi:10.1128/jb.184.22.6301-6315.2002. PMC 151953. PMID 12399500.
- ^ Mohamed ME, Zaar A, Ebenau-Jehle C, Fuchs G (March 2001). "Reinvestigation of a new type of aerobic benzoate metabolism in the proteobacterium Azoarcus evansii". Journal of Bacteriology. 183 (6): 1899–908. doi:10.1128/JB.183.6.1899-1908.2001. PMC 95084. PMID 11222587.
External links edit
- Benzoyl-CoA+2,3-dioxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
