Bacteroid-trp RNA motif

The Bacteroid-trp RNA motif is a conserved RNA element detected by bioinformatics.[1] It is found in the phylum Bacteroidota in the apparent 5' untranslated regions of genes that encode enzymes used in the synthesis of the amino acid tryptophan. A short open reading frame is found within the motif that encodes at least two tryptophan codons. Similar motifs have been identified regulating tryptophan genes in Pseudomonadota (see trp operon), but not in Bacteroidota. However, the Bacteroid-trp RNA motif likely operates via the same mechanism of attenuation.

Bacteroidete tryptophan peptide leader RNA
Conserved secondary structure of Bacteroid-trp RNA.
Identifiers
SymbolBacteroid-trp
RfamRF01692
Other data
RNA typecis-regulatory element; leader
Domain(s)Bacteroidota
PDB structuresPDBe

References

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  1. ^ Weinberg Z, Wang JX, Bogue J, et al. (March 2010). "Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea and their metagenomes". Genome Biol. 11 (3): R31. doi:10.1186/gb-2010-11-3-r31. PMC 2864571. PMID 20230605.
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