Azapropazone

Azapropazone
Clinical data
Trade names	Rheumox
AHFS/Drugs.com	International Drug Names
ATC code	M01AX04 (WHO) ;
Legal status
Legal status	UK: POM (Prescription only);
Pharmacokinetic data
Elimination half-life	20 hours
Identifiers
	IUPAC name (RS)-5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione;
CAS Number	13539-59-8 ;
PubChem CID	26098;
ChemSpider	24310 ;
UNII	K2VOT966ZI;
KEGG	D02966 ;
ChEBI	CHEBI:38010 ;
ChEMBL	ChEMBL1231131 ;
CompTox Dashboard (EPA)	DTXSID6045408 ;
ECHA InfoCard	100.033.543
Chemical and physical data
Formula	C16H20N4O2
Molar mass	300.362 g·mol−1
3D model (JSmol)	Interactive image;
Chirality	Racemic mixture
	SMILES O=C3N/1N(c2c(\N=C\1N(C)C)ccc(c2)C)C(=O)C3CCC;
	InChI InChI=1S/C16H20N4O2/c1-5-6-11-14(21)19-13-9-10(2)7-8-12(13)17-16(18(3)4)20(19)15(11)22/h7-9,11H,5-6H2,1-4H3 ; Key:MPHPHYZQRGLTBO-UHFFFAOYSA-N ;
	(what is this?) (verify)

Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID). It is manufactured by Goldshield under the tradename Rheumox.^[1]

It was available in the UK as a prescription-only drug, with restrictions due to certain contra-indications and side-effects.^[2] Azopropazone has now been discontinued in the British National Formulary.

Azapropazone has a half-life of approximately 20 hours in humans and is not extensively metabolized.^[3]

References

^ "Rheumox Capsules". South Africa Electronic Package Inserts. Archived from the original on 2008-05-15. Retrieved 2008-08-18.
^ "Azapropazone". Patient UK. Archived from the original on 12 April 2009.
^ Jones CJ (1976). "The pharmacology and pharmacokinetics of azapropazone - a review". Current Medical Research and Opinion. 4 (1): 3–16. doi:10.1185/03007997609109277. PMID 770078.

This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it.

[1] "Rheumox Capsules". South Africa Electronic Package Inserts. Archived from the original on 2008-05-15. Retrieved 2008-08-18.

[2] "Azapropazone". Patient UK. Archived from the original on 12 April 2009.

[pmid770078-3] Jones CJ (1976). "The pharmacology and pharmacokinetics of azapropazone - a review". Current Medical Research and Opinion. 4 (1): 3–16. doi:10.1185/03007997609109277. PMID 770078.

[1]

[2]

[3]