The Women's 400 metres hurdles at the 2010 Commonwealth Games as part of the athletics programme was held at the Jawaharlal Nehru Stadium on Saturday 9 October and Sunday 10 October 2010.
Records edit
| World Record | 52.34 | Yuliya Nosova | RUS | Tula, Russia | 8 August 2003 |
| Games Record | 53.82 | Jana Pittman | AUS | Melbourne, Australia | 2006 |
Round 1 edit
First 3 in each heat (Q) and 2 best performers (q) advance to the Final.
Heat 1 edit
| Rank | Lane | Name | Reaction Time | Result | Notes |
|---|---|---|---|---|---|
| 1 | 7 |  Nickiesha Wilson (JAM) |
0.310 | 56.51 | Q |
| 2 | 3 |  Lauren Boden (AUS) |
0.207 | 56.72 | Q |
| 3 | 6 |  Carole Kaboud Mebam (CMR) |
0.213 | 56.95 | Q, SB |
| 4 | 4 |  Maureen Maiyo (KEN) |
0.237 | 59.16 | q |
| 5 | 5 |  Jauna Murmu (IND) |
59.86 |
Heat 2 edit
| Rank | Lane | Name | Reaction Time | Result | Notes |
|---|---|---|---|---|---|
| 1 | 6 |  Muizat Odumosu (NGR) |
0.240 | 55.86 | Q |
| 2 | 7 |  Eilidh Child (SCO) |
0.202 | 56.16 | Q |
| 3 | 3 |  Meghan Beesley (ENG) |
0.222 | 56.95 | Q |
| 4 | 4 | Florence Wasike (KEN) |
0.254 | 57.04 | q |
| 5 | 5 | Ashwini Akkunji (IND) |
59.49 | ||
| 6 | 8 |  Christine McMahon (NIR) |
0.239 | 1:01.27 |
Final edit
| Rank | Lane | Name | Reaction Time | Result | Notes |
|---|---|---|---|---|---|
 |
4 | Muizat Odumosu (NGR) |
0.246 | 55.28 | |
 |
5 | Eilidh Child (SCO) |
0.238 | 55.62 | |
 |
6 | Nickiesha Wilson (JAM) |
0.306 | 56.06 | |
| 4 | 7 | Lauren Boden (AUS) |
0.210 | 56.31 | |
| 5 | 9 | Carole Kaboud Mebam (CMR) |
0.354 | 57.61 | |
| 6 | 2 | Florence Wasike (KEN) |
0.254 | 57.75 | |
| 7 | 8 | Meghan Beesley (ENG) |
0.258 | 58.36 | |
| – | 3 | Maureen Maiyo (KEN) |
DSQ |