André Nussenzweig (born October 25, 1960) is an American molecular biologist (former physicist). He studies the mechanisms that maintain genomic stability and prevent cancer. He is a distinguished investigator and chief of the Laboratory of Genome Integrity within the Center for Cancer Research at the National Cancer Institute. He is a member of the US National Academy of Medicine, the US National Academy of Sciences and American Academy of Arts and Sciences.[1]
André Nussenzweig | |
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Born | October 25, 1960 |
Alma mater |
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Awards |
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Scientific career | |
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Institutions | National Institutes of Health |
Early life
editHe is the youngest son of Victor and Ruth Nussenzweig[2] who worked on the development of malaria vaccines[3] André Nussenzweig did his undergraduate studies in physics at New York University,[4] and subsequently obtained a Ph.D. in physics at Yale University in 1989.
Career
editHe worked two years in Serge Haroche's laboratory as a postdoctoral fellow at the Ecole Normale Superieure in Paris, France. In 1992, he began research on DNA repair in the Department of Medical Physics at Memorial Sloan-Kettering Cancer Center. There, he established a long-standing collaboration with his brother Michel C. Nussenzweig at Rockefeller University, working on immunoglobulin class-switch recombination.[5] In 1998, he established an independent research group within the Experimental Immunology Branch[6] at the National Cancer Institute at the National Institutes of Health in Bethesda Maryland. In 2011, he started his own department at the National Cancer Institute named the Laboratory of Genome Integrity.[7] His research provides insight into various mutagenic sources, risk factors, and mechanisms underlying cancer.[8]
Personal life
editNussenzweig lives in Washington DC.[citation needed]
Recognition
editPartial list:
- Ellison Medical Foundation Senior Scholar in Aging[9]
- 2007 - the Arthur S. Flemming Award[10][11]
- 2016 - NIH Distinguished Investigator[11]
- 2021 - Long School of Medicine Distinguished Scholar Award
- 2021 - the Basser Global Prize for BRCA Research[12]
- 2024 -
Environmental Mutagenesis and Genomics Society Professional Award[13]
- 2024 - HHS Career Achievement Award[14]
- 2024 - Bert and Natalie Vallee Award in Biomedical Science[15]
Organizations
edit- Scientific Advisory Committee of Stand Up To Cancer[16]
- European Molecular Biology Organization[17]
- U.S. National Academy of Medicine[18]
- U.S. National Academy of Sciences[19]
- American Academy of Arts and Sciences[20]
References
edit- ^ "Andre Nussenzweig's CCR page".
- ^ "A Fresh Start, Back in Brazil, at 85". 25 June 2013.
- ^ Hoffman, Stephen L. (2018). "Ruth Nussenzweig (1928–2018) Malaria Vaccine and Immunology Pioneer". The American Journal of Tropical Medicine and Hygiene. 99 (2): 253–254. doi:10.4269/ajtmh.18-1928. PMC 6090352. PMID 29968552.
- ^ "Andre Nussenzweig, PhD".
- ^ Petersen, S.; Casellas, R.; Reina-San-Martin, B.; Chen, H. T.; Difilippantonio, M. J.; Wilson, P. C.; Hanitsch, L.; Celeste, A.; Muramatsuk, M.; Pilch, D. R.; Redon, C.; Ried, T.; Bonner, W. M.; Honjo, T.; Nussenzweig, M. C.; Nussenzweig, A. (2001). "AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching". Nature. 414 (6864): 660–665. Bibcode:2001Natur.414..660P. doi:10.1038/414660a. PMC 4729367. PMID 11740565.
- ^ "Experimental Immunology Branch".
- ^ "Andre Nussenzweig's biography".
- ^ "andre Nussenzweig". scholar.google.com.
- ^ "EMF: announcements". www.ellison-med-fn.org.
- ^ "Arthur S. Flemming Awards | The Trachtenberg School of Public Policy & Public Administration | The George Washington University". The Trachtenberg School of Public Policy & Public Administration.
- ^ a b "Awards and Accolades of CCR awardees".
- ^ "Basser Center for BRCA Awards 2021 Basser Global Prize to National Cancer Institute's Andre Nussenzweig". 15 July 2021.
- ^ "2024 EMGS Professional Award". 14 Feb 2024.
- ^ "CCR researchers receive a range of HHS awards". 26 April 2024.
- ^ "ASBMB names 2025 award winners". 20 August 2024.
- ^ "Scientific Advisory Committee (SAC)" (PDF).
- ^ "Find people in the EMBO Communities". people.embo.org.
- ^ "National Academy of Medicine Elects 100 New Members". 21 October 2019.
- ^ "2023 NAS Election". 2 May 2023.
- ^ "Andre Nussenzweig and Sandra Wolin elected to American Academy of Arts and Science". 19 April 2023.