Aditoprim is an antibacterial dihydrofolate reductase inhibitor.[1]

Aditoprim
Names
Preferred IUPAC name
5-{[4-(Dimethylamino)-3,5-dimethoxyphenyl]methyl}pyrimidine-2,4-diamine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C15H21N5O2/c1-20(2)13-11(21-3)6-9(7-12(13)22-4)5-10-8-18-15(17)19-14(10)16/h6-8H,5H2,1-4H3,(H4,16,17,18,19)
    Key: QBQMXWZTRRWPGK-UHFFFAOYSA-N
  • InChI=1/C15H21N5O2/c1-20(2)13-11(21-3)6-9(7-12(13)22-4)5-10-8-18-15(17)19-14(10)16/h6-8H,5H2,1-4H3,(H4,16,17,18,19)
    Key: QBQMXWZTRRWPGK-UHFFFAOYAE
  • CN(C)C1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC
Properties
C15H21N5O2
Molar mass 303.366 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References

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  1. ^ Then, RL; Keller, M (1988). "Properties of aditoprim, a new antibacterial dihydrofolate reductase inhibitor". Zentralblatt für Veterinärmedizin Reihe B. 35 (2): 114–20. doi:10.1111/j.1439-0450.1988.tb00476.x. PMID 3420982.