The Actino-ugpB RNA motif is a conserved RNA structure that was discovered by bioinformatics.[1]
Actino-ugpB motifs are found in strains of the species Gardnerella vaginalis, within the phylum Actinomycetota.
| Actino-ugpB | |
|---|---|
 Consensus secondary structure and sequence conservation of Actino-ugpB RNA | |
| Identifiers | |
| Symbol | Actino-ugpB |
| Rfam | RF02927 |
| Other data | |
| RNA type | Gene; sRNA |
| SO | SO:0001263 |
| PDB structures | PDBe |
It is ambiguous whether Actino-ugpB RNAs function as cis-regulatory elements or whether they operate in trans. Many of the RNAs are upstream of the gene 'ugpB', which encodes a protein putatively involved in sugar transport. However, several of the RNAs are not located upstream of a protein-coding gene. Structurally, the motif consists of two hairpins with conserved nucleotides located in the stems and outside of the hairpins, but not in their terminal loops.
References
edit- ^ Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR (October 2017). "Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions". Nucleic Acids Res. 45 (18): 10811–10823. doi:10.1093/nar/gkx699. PMC 5737381. PMID 28977401.
  | This bioinformatics-related article is a stub. You can help Wikipedia by expanding it. |