In organic chemistry, AD-mix is a commercially available mixture of reagents that acts as an asymmetric catalyst for various chemical reactions, including the Sharpless asymmetric dihydroxylation of alkenes. The two letters AD, stand for asymmetric dihydroxylation. The mix is available in two variations, "AD-mix α" and "AD-mix β" following ingredient lists published by Barry Sharpless.[1]

The mixes contain:

DHQ2PHAL AD-mix
DHQD2PHAL AD-mix

References

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  1. ^ ^ Sharpless, K. B., et al. J. Org. Chem. 1992, 57, 2768-2771. (doi:10.1021/jo00036a003)
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  • Catalytic Asymmetric Dihydroxylation of Alkenes at Imperial College London Link