Acylphosphatase-2 is an enzyme that in humans is encoded by the ACYP2 gene.[5][6]

ACYP2
Identifiers
AliasesACYP2, ACYM, ACYP, acylphosphatase 2
External IDsOMIM: 102595; MGI: 1922822; HomoloGene: 41776; GeneCards: ACYP2; OMA:ACYP2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_029344

RefSeq (protein)

NP_083620

Location (UCSC)Chr 2: 53.97 – 54.31 MbChr 11: 30.46 – 30.6 Mb
PubMed search[3][4]
Wikidata
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Function

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Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170634Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000060923Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Modesti A, Raugei G, Taddei N, Marzocchini R, Vecchi M, Camici G, Manao G, Ramponi G (Dec 1993). "Chemical synthesis and expression of a gene coding for human muscle acylphosphatase". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1216 (3): 369–74. doi:10.1016/0167-4781(93)90003-v. PMID 8268218.
  6. ^ a b "Entrez Gene: ACYP2 acylphosphatase 2, muscle type".
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Further reading

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