6-phospho-β-galactosidase

The enzyme 6-phospho-β-galactosidase (EC 3.2.1.85) catalyzes the following reaction:

6-Phospho-β-galactosidase
Identifiers
EC no.3.2.1.85
CAS no.37237-42-6
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins
a 6-phospho-β-D-galactoside + H2O 6-phospho-D-galactose + an alcohol

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name is 6-phospho-β-D-galactoside 6-phosphogalactohydrolase. Other names in common use include phospho-β-galactosidase, β-D-phosphogalactoside galactohydrolase, phospho-β-D-galactosidase, and 6-phospho-β-D-galactosidase. This enzyme participates in galactose metabolism.

Structural studies

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As of 2007, four structures have been solved for this class of enzymes, with PDB accession codes 1PBG, 2PBG, 3PBG, and 4PBG.

References

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  • Hengstenberg W, Penberthy WK, Morse ML (1970). "Purification of the staphylococcal 6-phospho-β-D-galactosidase". Eur. J. Biochem. 14 (1): 27–32. doi:10.1111/j.1432-1033.1970.tb00256.x. PMID 5447434.