54321 may refer to:
- 54321, a 2016 Tamil-language film
- "5-4-3-2-1", a song by Manfred Mann
- 5-4-3 rule or 5-4-3-2-1 rule, an Ethernet design guideline
- Countdown, a sequence of backward counting towards a scheduled event
- "54321", a 2022 song by Offset
This disambiguation page lists articles associated with the same number.
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