23S rRNA (guanine2445-N2)-methyltransferase

23S rRNA (guanine2445-N2)-methyltransferase (EC 2.1.1.173, ycbY (gene), rlmL (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:23S rRNA (guanine2445-N2)-methyltransferase.[1] This enzyme catalyses the following chemical reaction

23S rRNA (guanine2445-N2)-methyltransferase
Identifiers
EC no.2.1.1.173
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
S-adenosyl-L-methionine + guanine2445 in 23S rRNA S-adenosyl-L-homocysteine + N2-methylguanine2445 in 23S rRNA

The enzyme methylates 23S rRNA in vitro.

References

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  1. ^ Lesnyak DV, Sergiev PV, Bogdanov AA, Dontsova OA (November 2006). "Identification of Escherichia coli m2G methyltransferases: I. the ycbY gene encodes a methyltransferase specific for G2445 of the 23 S rRNA". Journal of Molecular Biology. 364 (1): 20–5. doi:10.1016/j.jmb.2006.09.009. PMID 17010378.
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