Two-time defending champion Andrew Lapthorne and his partner Dylan Alcott defeated the other nine-time defending champion David Wagner and his partner Bryan Barten in the final, 6–7(5–7), 6–1, [10–6] to win the quad doubles wheelchair tennis title at the 2019 US Open. Alcott completed the Grand Slam and the career Golden Slam with the win.
| Wheelchair quad doubles | |
|---|---|
| 2019 US Open | |
| Champions |  Dylan Alcott Andrew Lapthorne |
| Runners-up |  Bryan Barten David Wagner |
| Score | 6–7(5–7), 6–1, [10–6] |
Seeds edit
Dylan Alcott / 
Andrew Lapthorne (champions)
Bryan Barten / David Wagner (final)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Bracket edit
| Final | ||||||
| 1 | Dylan Alcott Andrew Lapthorne
| 65 | 6 | [10] | ||
| 2 | Bryan Barten David Wagner
| 77 | 1 | [6] | ||