Christopher Eubanks and Evan King were the defending champions but only King chose to defend his title, partnering Nathan Pasha. King lost in the first round to Thanasi Kokkinakis and Matt Reid.
| Doubles | |
|---|---|
| 2018 Monterrey Challenger | |
| Champions |  Marcelo Arévalo Jeevan Nedunchezhiyan |
| Runners-up | Leander Paes Miguel Ángel Reyes-Varela |
| Score | 6–1, 6–4 |
Marcelo Arévalo and Jeevan Nedunchezhiyan won the title after defeating Leander Paes and Miguel Ángel Reyes-Varela 6–1, 6–4 in the final.
Seeds edit
Leander Paes / 
Miguel Ángel Reyes-Varela (final)
Gerard Granollers / Marcel Granollers (quarterfinals)
Marcelo Arévalo / Jeevan Nedunchezhiyan (champions)
Robert Galloway / Jackson Withrow (first round)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 | L Paes MÁ Reyes-Varela
| 6 | 6 | ||||||||||||||||||||||||
 D Ferrer P Martínez
| 3 | 4 | 1 | L Paes MÁ Reyes-Varela
| 64 | 6 | [10] | ||||||||||||||||||||
 A Behar R Quiroz
| 6 | 4 | [11] | A Behar R Quiroz
| 77 | 4 | [5] | ||||||||||||||||||||
 G Melzer J Melzer
| 4 | 6 | [9] | 1 | L Paes MÁ Reyes-Varela
| 64 | 7 | [10] | |||||||||||||||||||
| 4 |  R Galloway J Withrow
| 6 | 4 | [10] |  T Kokkinakis M Reid
| 77 | 5 | [8] | |||||||||||||||||||
| WC | L Gómez J Hernández-Fernández
| 4 | 6 | [12] | WC | L Gómez J Hernández-Fernández
| 4 | 4 | |||||||||||||||||||
| T Kokkinakis M Reid
| 6 | 6 | T Kokkinakis M Reid
| 6 | 6 | ||||||||||||||||||||||
| E King N Pasha
| 4 | 0 | 1 | L Paes MÁ Reyes-Varela
| 1 | 4 | |||||||||||||||||||||
 P Lorenzi LD Martínez
| 6 | 6 | 3 | M Arévalo J Nedunchezhiyan
| 6 | 6 | |||||||||||||||||||||
| WC | G López Villaseñor L Patiño
| 3 | 3 | P Lorenzi LD Martínez
| 3 | 4 | |||||||||||||||||||||
A Menéndez Maceiras M Vervoort
| 2 | 65 | 3 | M Arévalo J Nedunchezhiyan
| 6 | 6 | |||||||||||||||||||||
| 3 | M Arévalo J Nedunchezhiyan
| 6 | 77 | 3 | M Arévalo J Nedunchezhiyan
| 6 | 711 | ||||||||||||||||||||
 A Begemann F Polášek
| 6 | 7 | A Begemann F Polášek
| 3 | 69 | ||||||||||||||||||||||
G Escobar S Galdós
| 3 | 5 | A Begemann F Polášek
| 6 | 3 | [10] | |||||||||||||||||||||
| WC | E Nava M Sánchez
| 2 | 4 | 2 | G Granollers M Granollers
| 4 | 6 | [3] | |||||||||||||||||||
| 2 | G Granollers M Granollers
| 6 | 6 | ||||||||||||||||||||||||