James Cerretani and Philipp Oswald were the defending champions, but Cerretani chose to compete in Sofia instead. Oswald played alongside Treat Huey, but lost in the first round to Alessandro Motti and Stefano Travaglia.
| Doubles | |
|---|---|
| 2018 Ecuador Open Quito | |
| Champions |  Nicolás Jarry Hans Podlipnik-Castillo |
| Runners-up |  Austin Krajicek Jackson Withrow |
| Score | 7–6(8–6), 6–3 |
Nicolás Jarry and Hans Podlipnik-Castillo won the title, defeating Austin Krajicek and Jackson Withrow in the final, 7–6(8–6), 6–3.
Seeds edit
Marcelo Demoliner / 
Purav Raja (first round)
Treat Huey / 
Philipp Oswald (first round)
Santiago González / Miguel Ángel Reyes Varela (quarterfinals)
Pablo Carreño Busta / 
Guillermo Durán (first round)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Draw edit
| First round | Quarterfinals | Semifinals | Final | ||||||||||||||||||||||||
| 1 |  M Demoliner P Raja
| 77 | 4 | [12] | |||||||||||||||||||||||
| WC |  D Descloix G Monfils
| 62 | 6 | [14] | WC | D Descloix G Monfils
| 6 | 7 | |||||||||||||||||||
| Alt |  F Gaio A Martin
| 1 | 5 |  V Estrella Burgos C Ruud
| 2 | 5 | |||||||||||||||||||||
| V Estrella Burgos C Ruud
| 6 | 7 | WC | D Descloix G Monfils
| 3 | 3 | |||||||||||||||||||||
| 3 |  S González MÁ Reyes Varela
| 6 | 6 | N Jarry H Podlipnik-Castillo
| 6 | 6 | |||||||||||||||||||||
| A Giannessi P Lorenzi
| 3 | 3 | 3 | S González MÁ Reyes Varela
| 77 | 4 | [6] | ||||||||||||||||||||
| Alt |  F Bagnis J Souza
| 0 | 62 | N Jarry H Podlipnik-Castillo
| 62 | 6 | [10] | ||||||||||||||||||||
| N Jarry H Podlipnik-Castillo
| 6 | 77 | N Jarry H Podlipnik-Castillo
| 78 | 6 | ||||||||||||||||||||||
| A Krajicek J Withrow
| 6 | 6 | A Krajicek J Withrow
| 66 | 3 | ||||||||||||||||||||||
 R Carballés Baena M Cecchinato
| 3 | 4 | A Krajicek J Withrow
| 6 | 77 | ||||||||||||||||||||||
| Alt |  S Galdós G Melzer
| 7 | 6 | Alt | S Galdós G Melzer
| 4 | 63 | ||||||||||||||||||||
| 4 | P Carreño Busta G Durán
| 5 | 4 | A Krajicek J Withrow
| 6 | 77 | |||||||||||||||||||||
 A Bury H-y Peng
| 3 | 5 | A Motti S Travaglia
| 4 | 65 | ||||||||||||||||||||||
| WC |  G Escobar R Quiroz
| 6 | 7 | WC | G Escobar R Quiroz
| 66 | 77 | [7] | |||||||||||||||||||
| A Motti S Travaglia
| 6 | 6 | A Motti S Travaglia
| 78 | 65 | [10] | |||||||||||||||||||||
| 2 |  T Huey P Oswald
| 4 | 4 | ||||||||||||||||||||||||