2005–06 Eerste Klasse was a Dutch association football season of the Eerste Klasse.
| Season | 2005–6 |
|---|---|
| Relegated | 2006–07 Tweede Klasse |
← 2004–05 2006–07 → | |
Saturday champions were:
- A: SV Huizen
- B: TOGR
- C: SSV '65
- D: VV Nunspeet
- E: Oranje Nassau Groningen
Sunday champions were:
- A: HVV Hollandia
- B: VUC Den Haag
- C: Blauw Geel '38
- D: RKSV Groene Ster
- E: SC Enschede
- F: Meppeler Sport Club