2-Ketoarginine methyltransferase

2-Ketoarginine methyltransferase (EC 2.1.1.243, mrsA (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:5-carbamimidamido-2-oxopentanoate S-methyltransferase.[1] This enzyme catalyses the following chemical reaction

2-Ketoarginine methyltransferase
Identifiers
EC no.2.1.1.243
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
S-adenosyl-L-methionine + 5-guanidino-2-oxopentanoate S-adenosyl-L-homocysteine + 5-guanidino-3-methyl-2-oxopentanoate

The enzyme is involved in production of the rare amino acid 3-methylarginine.

References

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  1. ^ Braun SD, Hofmann J, Wensing A, Ullrich MS, Weingart H, Völksch B, Spiteller D (April 2010). "Identification of the biosynthetic gene cluster for 3-methylarginine, a toxin produced by Pseudomonas syringae pv. syringae 22d/93". Applied and Environmental Microbiology. 76 (8): 2500–8. doi:10.1128/aem.00666-09. PMC 2849186. PMID 20190091.
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