2-Hydroxy-1,4-benzoxazin-3-one monooxygenase (EC 1.14.13.140, BX5 (gene), CYP71C3 (gene)) is an enzyme with systematic name 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one,NAD(P)H:oxygen oxidoreductase (N-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction
| 2-Hydroxy-1,4-benzoxazin-3-one monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.140 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O
2-Hydroxy-1,4-benzoxazin-3-one monooxygenase is involved in the biosynthesis of protective and allelopathic benzoxazinoids in some plants.
References
edit- ^ Bailey BA, Larson RL (March 1991). "Maize microsomal benzoxazinone N-monooxygenase". Plant Physiology. 95 (3): 792–6. doi:10.1104/pp.95.3.792. PMC 1077607. PMID 16668055.
- ^ Glawischnig E, Grün S, Frey M, Gierl A (March 1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses". Phytochemistry. 50 (6): 925–30. doi:10.1016/s0031-9422(98)00318-5. PMID 10385992.
External links
edit- 2-hydroxy-1,4-benzoxazin-3-one+monooxygenase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
