The 1995 USISL Premier League season was the 1st season of the new "fourth level" of American soccer following the re-organization of the old United States Interregional Soccer League at the end of 1994. The season began in April 1995 and ended in August 1995.
Richmond Kickers finished the season as national champions, beating Cocoa Expos 3–1 in the USISL Premier League Championship game. San Francisco All-Blacks United finished with the best regular season record in the league, winning 17 out of their 18 games, suffering just one loss, and finishing with a +42 goal difference.
The USISL Premier League format in 1995 was notable for not having tied games; instead, teams competed in a penalty shoot-out to decide a winner, with bonus points awarded as appropriate.