The 1972–73 Coupe de France was its 56th edition. It was won by Olympique Lyonnais which defeated FC Nantes in the Final.
| Tournament details | |
|---|---|
| Country |  France |
Round of 16 edit
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| FC Sochaux-Montbéliard (D1) | 4–4 (4–5 p) | Red Star (D1) | 3–1 | 1–3 |
| Olympique Lyonnais (D1) | 4–3 | Girondins de Bordeaux (D1) | 3–0 | 1–3 |
| Nîmes Olympique (D1) | 4–1 | Stade de Reims (D1) | 2–1 | 2–0 |
| Paris FC (D1) | 3–4 | FC Nantes (D1) | 2–4 | 1–0 |
| Olympique de Marseille (D1) | 2–1 | Lille OSC (D2) | 0–1 | 2–0 |
| AS Saint-Étienne (D1) | 7–0 | AC Arles (D2) | 3–0 | 4–0 |
| EDS Montluçon (D2) | 1–6 | Olympique Avignonnais (D2) | 0–4 | 1–2 |
| En Avant Guingamp (PH) | 0–8 | FC Rouen (D2) | 0–5 | 0–3 |
Quarter-finals edit
| Team 1 | Agg. | Team 2 | 1st leg | 2nd leg |
|---|---|---|---|---|
| Olympique de Marseille (D1) | 1–4 | Olympique Lyonnais (D1) | 1–0 | 0–4 |
| AS Saint-Étienne (D1) | 3–5 | FC Nantes (D1) | 2–0 | 1–5 |
| Nîmes Olympique (D1) | 5–4 | Red Star (D1) | 4–2 | 1–2 |
| FC Rouen (D2) | 2–6 | Olympique Avignonnais (D2) | 2–0 | 0–6 |
Semi-finals edit
First round
| Olympique Avignonnais (2) | 1–0 | Olympique Lyonnais (1) |
|---|---|---|
Edom  26' |
(Report) |
| Nîmes Olympique (1) | 0–0 | FC Nantes (1) |
|---|---|---|
| (Report) |
Second round
| Olympique Lyonnais (1) | 4–1 | Olympique Avignonnais (2) |
|---|---|---|
| Lhomme 10' Baeza 49'Trivić 73' (pen.)Lacombe 80' |
(Report) | Copé 21' |