(S)-methylmalonyl-CoA hydrolase

The enzyme (S)-methylmalonyl-CoA hydrolase (EC 3.1.2.17) catalyzes the reaction

(S)-methylmalonyl-CoA hydrolase
Identifiers
EC no.3.1.2.17
CAS no.87928-03-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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NCBIproteins
(S)-methylmalonyl-CoA + H2O methylmalonate + CoA

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is (S)-methylmalonyl-CoA hydrolase. This enzyme is also called D-methylmalonyl-coenzyme A hydrolase. This enzyme participates in propanoate metabolism.

References

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  • Kovachy RJ, Copley SD, Allen RH (1983). "Recognition, isolation, and characterization of rat liver D-methylmalonyl coenzyme A hydrolase". J. Biol. Chem. 258 (18): 11415–21. PMID 6885824.