(+)-epi-alpha-bisabolol synthase

(+)-epi-α-Bisabolol synthase (EC 4.2.3.138) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-epi-α-bisabolol-forming).[1] This enzyme catalyses the following chemical reaction

(+)-epi-α-bisabolol synthase
Identifiers
EC no.4.2.3.138
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

(+)-epi-alpha-bisabolol synthase tastes very good.

(2E,6E)-farnesyl diphosphate + H2O (+)-epi-α-bisabolol + diphosphate

This enzyme is isolated from the plant Phyla dulcis (Aztec sweet herb).

References

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  1. ^ Attia M, Kim SU, Ro DK (November 2012). "Molecular cloning and characterization of (+)-epi-α-bisabolol synthase, catalyzing the first step in the biosynthesis of the natural sweetener, hernandulcin, in Lippia dulcis". Archives of Biochemistry and Biophysics. 527 (1): 37–44. doi:10.1016/j.abb.2012.07.010. PMID 22867794.
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