(+)-beta-caryophyllene synthase

(+)-β-Caryophyllene synthase (EC 4.2.3.89, GcoA) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-β-caryophyllene-forming).[1] This enzyme catalyses the following chemical reaction:

(+)-β-caryophyllene synthase
Identifiers
EC no.4.2.3.89
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins
(2E,6E)-farnesyl diphosphate (+)-β-caryophyllene + diphosphate

This enzyme also converts the (+)-β-caryophyllene to (+)-caryolan-1-ol.

References

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  1. ^ Nakano C, Horinouchi S, Ohnishi Y (August 2011). "Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus". The Journal of Biological Chemistry. 286 (32): 27980–7. doi:10.1074/jbc.m111.265652. PMC 3151043. PMID 21693706.
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