The surname Étienne, also spelled Etienne and Ettienne, may refer to:
- Andre Ettienne (born 1990), Trinidadian footballer
- Charles-Guillaume Étienne (1778–1845), French dramatist and writer
- Clauvis Etienne (born 2003), Senegalese footballer
- Clifford Etienne (born 1972), American former heavyweight boxer
- Errol Étienne (born 1941), artist in many media, including watercolor
- Ophélie-Cyrielle Étienne (born 1990), French swimmer
- Roland Étienne (archaeologist) (born 1944), French archaeologist
- Ronald Etienne (born 1896), Grenadian cricketer
- Travis Etienne (born 1999), American football player
- Trevor Etienne, American football player
- Tyson Etienne (born 1999), American basketball player