William Sapp may refer to:
- William Fletcher Sapp (1824–1890), United States Attorney and Representative from Iowa
- William Frederick Sapp (1856–1917), American politician from Kansas
- William R. Sapp (1804–1875), U. S. Representative from Ohio
- William Sapp (serial killer) (born 1962), American serial killer
This disambiguation page lists articles about people with the same name.
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