William Martin Gelbart (September 11, 1945 - August 11, 2015) was an American geneticist and a professor of molecular and cellular biology at Harvard University. He was best known for his work with fly genetics, the discovery of decapentaplegic (dpp), and the formation of FlyBase.[1][2] He was a member of the National Advisory Council for the Human Genome Project.[3]

William Martin Gelbart
BornSeptember 11, 1945
DiedAugust 11, 2015(2015-08-11) (aged 69)
Alma materBrooklyn College, University of Wisconsin
AwardsGeorge W. Beadle Award (2010)
Scientific career
FieldsGenetics
InstitutionsHarvard University

Early life and education edit

Gelbart was born in Brooklyn, New York. He earned his B.S. in biology from Brooklyn College in 1966 after attending Harpur College at Binghampton University from 1962 to 1963.[4] He received a PhD in genetics from the University of Wisconsin–Madison in 1971 with Allen S. Fox.[1]

Career and research edit

Gelbart did his postdoctoral work with Edward B. Lewis at Caltech and Art Chovnick at the University of Connecticut. He began his career at Harvard University in 1976 before becoming a full professor in 1983. His research was focused on molecular basis of pattern formation using the fruit fly as a model system. Using transvection, his group identified decapentaplegic, an locus containing an ortholog of human bone morphogenetic proteins. [5][1] Gelbart was a major leader in consolidating the findings of the Drosophila community into FlyBase along with Michael Ashburner, Rachel Drysdale, Gerry Rubin, Thom Kaufman and Kathy Matthews.[2]

References edit

  1. ^ a b c "WILLIAM M. GELBART SEPTEMBER 11, 1945 - AUGUST 11, 2015". Harvard University - Department of Molecular & Cellular Biology. 20 October 2015.
  2. ^ a b Wharton, Kristi (December 2015). "William Martin Gelbart 1945–2015". Nature Genetics. 47 (12): 1372. doi:10.1038/ng.3455. PMID 26620108.
  3. ^ says, Genes to Genomes: a blog from the Genetics Society of America (16 August 2015). "In Memoriam: Bill Gelbart". Genes to Genomes.
  4. ^ Matthew Meselson, Norbert Perrimon and Daniel Hartl (Chair). "Tribute to the life and service of William M. Gelbert", Harvard.edu website, 2 February 2016.
  5. ^ Spencer, Forrest A.; Hoffmann, F.Michael; Gelbart, William M. (March 1982). "Decapentaplegic: A gene complex affecting morphogenesis in Drosophila melanogaster". Cell. 28 (3): 451–461. doi:10.1016/0092-8674(82)90199-4. PMID 6804094. S2CID 24558891.