WRU may refer to:
- Welsh Rugby Union, sports association in Wales
- Waikato Rugby Union, sports association in Waikato, New Zealand
- Wesleyan Reform Union, Methodist church group in Britain
- WRU, station code for West Ruislip station, Hillingdon, Greater London, UK
- Western Reserve University, now part of Case Western Reserve University in Cleveland, Ohio
This disambiguation page lists articles associated with the title WRU.
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