- Key
| Abbreviation | Meaning |
|---|---|
| ED | Player acquired via the 2021 NHL expansion draft |
| T | Player acquired via trade |
| FA | Player acquired via free agency |
| W | Player claimed via waivers |
| RS | Player re-signed to a contract |
| ELC | Player signed to an entry-level contract |
- Table
| Player no. | Contract no. | Player[a][b] | Via | Term[c] | Date | Article status | Press release |
|---|---|---|---|---|---|---|---|
| 1 | 1 | Luke Henman | ELC | 3-year | May 12, 2021 | Stub | [1] |
| 2–4 | 2–4 | Adam Larsson | FA | 4-year | July 21, 2021 | B | [2] |
| Jamie Oleksiak | 5-year | C | |||||
| Chris Driedger | 3-year | C | |||||
| 5 | — | Jeremy Lauzon | ED | — | Start | — | |
| Will Borgen | Stub | ||||||
| Dennis Cholowski | Start | ||||||
| 2–4 | Chris Driedger | C | |||||
| 5 | Cale Fleury | Start | |||||
| Joey Daccord |  GA
| ||||||
| Yanni Gourde | C | ||||||
| Jared McCann | C | ||||||
| Morgan Geekie | Start | ||||||
| Gavin Bayreuther | Start | ||||||
| Nathan Bastian | Stub | ||||||
| Jordan Eberle | B | ||||||
| Colin Blackwell | Start | ||||||
| Carsen Twarynski | Start | ||||||
| Brandon Tanev | GA
| ||||||
| Vitek Vanecek | C | ||||||
| Tyler Pitlick | C | ||||||
| John Quenneville | Start | ||||||
| Joonas Donskoi | C | ||||||
| 2–4 | Jamie Oleksiak | C | |||||
| 5 | Carson Soucy | Start | |||||
| Calle Jarnkrok | Start | ||||||
| Vince Dunn | GA
| ||||||
| Mason Appleton | Start | ||||||
| Haydn Fleury | Start | ||||||
| Mark Giordano | GA
| ||||||
| 2–4 | Adam Larsson | B | |||||
| 5 | Kurtis MacDermid | Start | |||||
| Alexander True | C | ||||||
| Kole Lind | C | ||||||
| 32 | 5 | Alexander Wennberg | FA | 3-year | July 28, 2021 | Start | [3] |
| 33 | 6 | Jaden Schwartz | 5-year | GA |
[4] | ||
| 34 | 7 | Philipp Grubauer | 6-year | B | [5] | ||
| 35 | 8 | Connor Carrick | FA, ELC | 1-year | August 4, 2021 | Start | [6] |
| 5 | 9 | Alexander True | RS, ELC | C | [7] | ||
| 10 | Will Borgen | RS | 2-year | August 5, 2021 | Stub | [8] | |
| 36 | 11 | Marcus Johansson | FA | 1-year | August 6, 2021 | Start | [9] |
| 5 | 12 | Vince Dunn | RS | 2-year | GA |
[10] | |
| 13 | Cale Fleury | 1-year | August 13, 2021 | Start | — | ||
| 14 | Carsen Twarynski | Start | |||||
| 37 | 15 | Antoine Bibeau | FA | 1-year | August 20, 2021 | Start | [11] |
| 38 | 16 | Gustav Olofsson | August 25, 2021 | Stub | [12] | ||
| 39 | 17 | Riley Sheahan | September 1, 2021 | Start | [13] | ||
| 5 | 18 | Dennis Cholowski | RS | September 7, 2021 | Start | [14] | |
| 40 | 19 | Ryan Donato | FA | September 13, 2021 | Start | [15] | |
| 41 | 20 | Max McCormick | September 29, 2021 | Start | — | ||
| 42 | — | Alex Barre-Boulet | W | — | October 11, 2021 | Start | |
| 43 | Austin Czarnik | February 8, 2021 | Stub | ||||
| 5 | Dennis Cholowski | February 9, 2021 | Start |
- Notes