U42 or U-42 may refer to:
- German submarine U-42, various vessels
- Great ditrigonal dodecicosidodecahedron
- HMS Modeste (U42), a sloop of the Royal Navy
- Small nucleolar RNA SNORD42
- South Valley Regional Airport, serving Salt Lake City, Utah, United States
- U42, a line of the Dortmund Stadtbahn
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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