The following highways in Virginia have been known as State Route 12:
- State Route 12, 1918–1933, originally Abingdon to Suffolk, now mainly U.S. Route 58#Virginia
- State Route 12, 1933 – mid-1930s, now U.S. Route 220 in Virginia from Troutville to Clifton Forge
- State Route 12, 1935–1953, now U.S. Route 340 in Virginia from Greenville to Berryville
This disambiguation page lists articles about roads and streets with the same name.
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