List of highways numbered 381

The following highways are numbered 381:

Brazil

• BR-381

Canada

• Newfoundland and Labrador Route 381
• Quebec Route 381
• Saskatchewan Highway 381

Cuba

• Road of Jamaica (Cuba) (2–381)

Japan

• Japan National Route 381

United States

• Interstate 381
• Georgia State Route 381 (former)
• Kentucky Route 381
• Maryland Route 381
• New York State Route 381 (former)
• North Carolina Highway 381
• Pennsylvania Route 381
• Puerto Rico Highway 381
• South Carolina Highway 381
• Tennessee State Route 381
• Virginia State Route 381

Preceded by 380

Lists of highways 381

Succeeded by 382