Monocarboxylate transporter 6

(Redirected from SLC16A5)

Monocarboxylate transporter 6 (MCT6) is a protein in humans that is encoded by the SLC16A5 gene.[5]

SLC16A5
Identifiers
AliasesSLC16A5, MCT5, MCT6, solute carrier family 16 member 5, Monocarboxylate transporter 6
External IDsOMIM: 603879; MGI: 2443515; HomoloGene: 20985; GeneCards: SLC16A5; OMA:SLC16A5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001271765
NM_004695
NM_001369668

NM_001080934
NM_001359606
NM_001359608
NM_001359609

RefSeq (protein)

NP_001258694
NP_004686
NP_001356597

NP_001074403
NP_001346535
NP_001346537
NP_001346538

Location (UCSC)Chr 17: 75.09 – 75.11 MbChr 11: 115.35 – 115.37 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a member of the monocarboxylate transporter family and the major facilitator superfamily. The encoded protein is localized to the cell membrane and acts as a proton-linked transporter of bumetanide. Transport by the encoded protein is inhibited by four loop diuretics, nateglinide, thiazides, probenecid, and glibenclamide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].

References

edit
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000170190Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000045775Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Solute carrier family 16, member 5 (monocarboxylic acid transporter 6)".