Isonicotinamide (pyridine-4-carboxamide) is the amide form of isonicotinic acid. It is an isomer of nicotinamide, which has the carboxamide group in the 3-position.[1]

Isonicotinamide
Names
Preferred IUPAC name
Pyridine-4-carboxamide
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.014.479 Edit this at Wikidata
UNII
  • InChI=1S/C6H6N2O/c7-6(9)5-1-3-8-4-2-5/h1-4H,(H2,7,9) ☒N
    Key: VFQXVTODMYMSMJ-UHFFFAOYSA-N ☒N
  • InChI=1/C6H6N2O/c7-6(9)5-1-3-8-4-2-5/h1-4H,(H2,7,9)
    Key: VFQXVTODMYMSMJ-UHFFFAOYAE
  • c1cnccc1C(=O)N
Properties
C6H6N2O
Molar mass 122.127 g·mol−1
Melting point 155–157 °C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

It is soluble in water (191 g/L), and is also soluble in ethanol, DMSO, methanol, chloroform, chloroform/methanol mixtures, and dioxane (10 mg/L). This compound is used for material synthesis.[2]

Compounds in which the amide nitrogen is connected to another, and then doubly-bonded, are called isonicotinoylhydrazones.[3]

See also

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References

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  1. ^ PubChem. "Isonicotinamide". pubchem.ncbi.nlm.nih.gov. Retrieved 2020-07-25.
  2. ^ "Isonicotinamide | C6H6N2O | ChemSpider". www.chemspider.com. Retrieved 2020-07-25.
  3. ^ "isonicotinamide (CHEBI:6031)". www.ebi.ac.uk. Retrieved 2020-07-25.