Prolyl aminopeptidase

(Redirected from Proline iminopeptidase)

Prolyl aminopeptidase (EC 3.4.11.5, proline aminopeptidase, Pro-X aminopeptidase, cytosol aminopeptidase V, proline iminopeptidase) is an enzyme.[1][2][3] This enzyme catalyses the following chemical reaction

Prolyl aminopeptidase
Identifiers
EC no.3.4.11.5
CAS no.9025-40-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins
Release of N-terminal proline from a peptide

This enzyme requires Mn2+ ion to function.

References

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  1. ^ Sarid S, Berger A, Katchalski E (July 1962). "Proline iminopeptidase. II. Purification and comparison with iminodipeptidase (prolinase)". The Journal of Biological Chemistry. 237 (7): 2207–12. doi:10.1016/S0021-9258(19)63420-4. PMID 14497218.
  2. ^ Nordwig A, Mayer H (April 1973). "The cleavage of prolyl peptides by kidney peptidases. Detection of a new peptidase capable of removing N-terminal proline". Hoppe-Seyler's Zeitschrift für Physiologische Chemie. 354 (4): 380–3. doi:10.1515/bchm2.1973.354.1.380. PMID 4803482.
  3. ^ Turzynski A, Mentlein R (July 1990). "Prolyl aminopeptidase from rat brain and kidney. Action on peptides and identification as leucyl aminopeptidase". European Journal of Biochemistry. 190 (3): 509–15. doi:10.1111/j.1432-1033.1990.tb15603.x. PMID 2373079.
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