Preston Smith may refer to:
- Preston Smith (American football coach) (1871–1945), American football coach at Colgate University
- Preston Smith (linebacker) (born 1992), American football outside linebacker
- Preston Smith (governor) (1912–2003), Texas governor, 1969–1973
- Preston Smith (general) (1823–1863), Civil War Confederate general
- Preston Smith (Georgia state politician), Georgia state senator, 2002–2011
- Preston Smith (musician), singer/songwriter from Houston, Texas
- Lubbock Preston Smith International Airport, an airport in Texas, USA
This disambiguation page lists articles about people with the same name.
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