Paulo Santos may refer to:
- Paulo Santos (Portuguese footballer) (Paulo Jorge Silva Santos, born 1972), Portuguese football goalkeeper
- Paulo Futre (Paulo Jorge Santos Futre, born 1966), former Portuguese football winger
- Paulo Dos Santos (Cape Verdean footballer) (born 1973), Cape Verdean football midfielder
- Paulo Santos (Brazilian footballer) (born 1960), Brazilian former footballer
- Paulo Roberto Santos (born 1958), Brazilian footballer and manager