Michael McGuire or Mike McGuire may refer to:
- Michael McGuire (actor) (born 1934), American actor
- Michael McGuire (author), Australian author and columnist
- Michael McGuire (politician) (1926–2018), British Labour Party politician
- Michael J. McGuire (born 1947), environmental engineer and writer
- Michael T. McGuire (1929–2016), American psychiatrist
- Mick McGuire (born 1952), English footballer
- Mick McGuire (general), American major general
- Mike McGuire (baseball), American college baseball coach
- Mike McGuire (basketball) (born 1977), American college basketball coach
- Mike McGuire (politician) (born 1979), American politician
See also
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This disambiguation page lists articles about people with the same name.
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