Margaret of Denmark may refer to:
- Margaret Fredkulla (1080s–1130), wife of king Niels of Denmark
- Margarethe of Bohemia (1186–1212), aka Queen Dagmar, first wife of Valdemar II of Denmark
- Margaret Sambiria (1230–1282) of Pomerelia, wife of king Christopher I of Denmark
- Margaret I of Scandinavia (1353–1412), wife of Haakon VI of Norway, daughter of Valdemar IV of Denmark, mother of Olaf II of Denmark, also ruled Scandinavia as de facto queen regnant
- Margaret of Denmark, Queen of Scotland (1456–1486), queen-consort of James III of Scotland
- Princess Margaret of Denmark (1895–1992), wife of Prince René of Bourbon-Parma, daughter of Prince Valdemar of Denmark and mother of Queen Anne of Romania
- Princess Margaretha of Sweden (1899–1977), Princess of Denmark through her marriage to Prince Axel
- Margrethe II of Denmark (born 1940), Queen-regnant of Denmark (1972-2024)
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