Louise of Prussia (German: Luise von Preußen) may refer to:
- Princess Louise Dorothea of Prussia (1680–1705), daughter of Frederick I of Prussia and wife of Frederick I of Sweden
- Louisa Ulrika of Prussia (1720–1782), daughter of Frederick William I of Prussia and wife of Adolf Frederick of Sweden
- Princess Louise of Prussia (1770–1836), daughter of Prince Augustus Ferdinand of Prussia and wife of Prince Anton Radziwill
- Queen Louise of Prussia (1776–1810), daughter of Charles II, Grand Duke of Mecklenburg-Strelitz and wife of Frederick William III of Prussia
- Princess Louise of Prussia (1808–1870), daughter of Frederick William III of Prussia and wife of Prince Frederick of the Netherlands
- Princess Louise of Prussia (1829–1901), daughter of Prince Charles of Prussia and wife of Alexis, Landgrave of Hesse-Philippsthal-Barchfeld
- Princess Louise of Prussia (1838–1923), daughter of William I of Prussia (later German Emperor) and wife of Frederick I, Grand Duke of Baden
- Princess Louise Margaret of Prussia (1860–1917), daughter of Prince Frederick Charles of Prussia and wife of Prince Arthur, Duke of Connaught
- Princess Victoria Louise of Prussia (1892–1980), daughter of William II, German Emperor and wife of Ernest Augustus, Duke of Brunswick
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