A lock and key is a pair of devices used to secure an object or location from unauthorized access.
Lock and Key or Lock & Key may also refer to:
Arts, entertainment, and media edit
Film edit
- Taala Te Kunjee (Lock and Key), a 2017 Indian Punjabi-language film
Literature edit
- Lock and Key (novel), a 2008 novel by Sarah Dessen
- Lock and Key, a book series by Ridley Pearson
Music edit
Albums and EPs edit
- Lock & Key (album), a 2014 album by Cruel Hand
- Lock & Key, an EP by Wild Adriatic
Songs edit
- "Lock and Key" (Klymaxx song)
- "Lock and Key" (Rush song)
- "Lock and Key", a song by Nina Sky
- "Lock and Key", song by SNAFU from the album Situation Normal
Science edit
- Lock and key model, a model for the specificity of enzymes and other of biomolecules
- Memory protection, a computer memory protection technique