LGS may refer to:
Education
editSchools
edit- Lahore Grammar School
- Lanark Grammar School
- Langley Grammar School
- Larne Grammar School
- Leeds Grammar School
- Leicester Grammar School
- Limavady Grammar School
- Loughborough Grammar School, one of the Loughborough Endowed Schools
Other
edit- Liselere Geçiş Sınavı, the old name for OKS.
- Local gaming store. A store to play or purchase board games.
Entertainment
edit- Looking Glass Studios, a defunct computer game company
- La Grande Sophie, a French singer-songwriter
Science
edit- Laser guide star, an adaptive optics instrument used in Astronomy
- Leaky gut syndrome, an intestinal dysfunction
- LGS Innovations, a high-tech private company and former division of Bell Labs
- Latitudinal Gradients in Species diversity
- Lennox–Gastaut syndrome, a type of epilepsy
- Light Gauge Steel, also called cold-formed steel
Software
edit- Logitech Gaming Software, a driver style software for Logitech Gaming products