José Diego may refer to:

  • Diego José de Cádiz (1743–1801), a Spanish Capuchin friar and preacher from the Andalusia region.
  • José de Diego (1866–1918), a Puerto Rican statesman, journalist, poet, lawyer, and advocate for independence.
  • José Tormos Diego (1890–1977), a Puerto Rican politician who served as mayor of Ponce.
  • José Diego (footballer), (born 1954), a Spanish former footballer who played as a midfielder for Real Sociedad and the Spain national team.

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